College football best bets: Alabama-Ole Miss, Colorado-Oregon, OSU-Notre Dame, Clemson-FSU and more Week 4 LOCKS (09/21)

The Cover 3 crew shares their top against the spread and over-under plays for Week 4 in college football. After a brief recap of Week 3 results (1:00), the Week 4 breakdowns, previews and picks start with Thursday and Friday night action (7:26) before turning the attention to a loaded Saturday slate. Florida State-Clemson (16:37), Alabama-Ole Miss (19:43), Colorado-Oregon (24:37), Ohio State-Notre Dame (28:55) and Penn State-Iowa (34:05) are up first as some of the biggest games of the day, then the LOCKS board opens up for picks on USC-Arizona State (42:23), Kansas-BYU (44:42), TCU-SMU (46:20), Michigan-Rutgers (49:58), Auburn-Texas A&M (56:32), Illinois-FAU (58:05), Kansas State-UCF (1:01:12) and more. Finally, the underdogs to take straight up in MoneyLine Sprinkles (1:05:00). Cover 3 is available on Apple Podcasts, Spotify, Stitcher, Google Podcasts, Castbox and wherever else you listen to podcasts.  Get 20% off Cover 3 merch in the CBS Sports Store:  https://store.cbssports.com/collections/cover-3?utm_source=podcast-apple-com&utm_medium=web&utm_campaign=buy-our-merch&utm_content=cover-3-collection Watch Cover 3 on YouTube: https://www.youtube.com/cover3 Follow our hosts on Twitter: @Chip_Patterson, @TomFornelli, @DannyKanell, @BudElliott3 For more college football coverage from CBS Sports, visit https://www.cbssports.com/college-football/ To hear more from the CBS Sports Podcast Network, visit https://www.cbssports.com/podcasts/ To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices